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Project works and master theses
Dehydratisierung von 3-Hydroxypropionaldehyd zu Acrolein als Bestandteil eines Prozesses zur Produktion von Chemikalien aus nachwachsenden Rohstoffen
Contact: Dipl.-Ing. Sebastian Oehmke email: oehmke@tu-harburg.de phone:+49 40 42878 2847 fax:+49 40 42878-2909 Entwicklung von Mikrokomponenten für den analytischen Einsatz in der Zellkultur
Contact: Dipl.-Biotech. Mattias Wurm email: wurm@tu-harburg.de phone:+49 40 42878 2511 fax:+49 40 42878-2909 Schnellfiltration von Fermenterbrühen zur Untersuchung des Metabolismus
Contact: Dipl.-Ing. Julian da Luz email: daluz@tu-harburg.de phone:+49 40 42878 2511 fax:+49 40 42878-2909 Design of a multi-step enzymatic process
Contact: Dr. Eng. Inés Ardao Palacios email: ines.ardao@tu-harburg.de phone:+49 40 42878 3931 fax:+49 40 42878-2909 Biokonversion of glycerol to 3-Hydroxypropionaldehyd
Contact: Prof. Dr. An-Ping Zeng email: aze@tu-harburg.de phone:+49 40 42878 4183 fax:+49 40 42878-2909 Cell culture technologyContact: Prof. Dr. -Ing. Ralf Pörtner Im Bereich "Zellkulturtechnik" bieten wir in den folgenden Schwerpunkten Themen für Diplomarbeiten an:
Entwicklung von Festbettreaktoren fur die Kultur tierischer Zellen auf makroporösen Trägermaterialien; Einsatzgebiete: Produktion monoklonaler Antikörper, rekombinante adhärente Zellen, physiologische Untersuchungen an Tumorzellen, künstliche Organe (Leber) Entwicklung von Fütterungsstrategien und modellgestützte Prozessführung für Zellkulturen Kultivierung von Chondrozyten zur Erstellung eines implantierbaren Gelenkknorpelersatzes "in vitro" Continuous cultivation of lactic acid bacteriaContact: Prof. Dr. -Ing. Ralf Pörtner Continuous cultivation of immobilized lactic acid bacteria in a fixed-bed reactor There have been numerous studies on the conversion of sugars, including glucose, lactose and sucrose, to lactic acid and valuable secondary metabo-lites with lactic acid bacteria in different types of processes to achieve higher productivity. The fermentation by conventional methods that use cell suspen-sion in batch processes has several limitations, such as low productivity, product inhibition and also the variation from batch to batch. Cell immobilization techniques have become more important and popular because it gives many advantages compared to cell suspension culture such as maintenance of stable and active biocatalysts, accelerated reaction rates, high volumetric productivity, improved process control, reduced susceptibility of cells to con-tamination, improved production efficiency and no possibility of washout. The aim of this project is to optimize the performance of long-term cultures of lactic acid bacteria in a fixed-bed reactor system.
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